Part of Bree's storyline were Shirley Knight returning as Phyllis Van de Kamp, Bree's first mother-in-law, and Dakin Matthews appearing as Reverend Sykes, reverend at the local Presbyterian church.Part of Gabrielle's storyline were John Slattery playing Victor Lang, Gabrielle's new husband and the mayor of Fairview, Mike Farrell in the role of Milton Lang, Victor's father, Jeff Doucette portraying Father Crowley, priest at the local Catholic church, Justine Bateman playing Ellie Leonard, a drug dealer who rents a room in the Solises' house, and Jesse Metcalfe reappearing as John Rowland, Gabrielle's ex-lover and former gardener.
The first part, "Something's Coming", aired on December 2, 2007.
Seven additional episodes were produced for the fourth season after the strike, the first of which aired on April 13, 2008.
The series was released on a five-disc DVD box set by ABC Studios on September 2, 2008 in Region 1, Joe Keenan, one of the three executive producers during the third season, as well as writer of the critically acclaimed season episode "Bang", did not return for season four as executive producer, but as consulting producer.
Replacing Keenan, and joining Marc Cherry and George W.
Rachel Fox was promoted to regular after guest starring in several episodes in the previous season as Kayla Huntington Scavo, Tom's mischievous daughter and the result of an affair he had before meeting Lynette.
This season featured many established and new guest stars.
The final two episodes served as a two-part finale and were aired consecutively on May 18, 2008.
A total of 17 episodes aired as part of the season, with one recap special airing on September 23, 2007.
Dana Delany is introduced in the role of Katherine Mayfair, whose mysterious arc is the season's main storyline.